Why morphine causes constipation?

QuestionsCategory: QuestionsWhy morphine causes constipation?
Biology Ease Staff asked 2 years ago
  • Morphine has spasmogenic action on the smooth muscles of G.LT.
  • It causes constriction of the sphincters and a decreases in the peristaltic movements of G.I.T.
  • This action of morphine results in stagnation of intestinal contents causing maximum absorption of water and drying of fecal matter.
  • Morphine reduces the sensitivity of intestinal walls to defecation reflexes.
  • The above actions of morphine cause constipation.
  • Tincture of opium contains morphine which possesses the constipating action.
  • Hence, it is used in diarrhea.